Tuesday, July 24, 2012

WASHINGTON: Scientists claim to have developed the world's first complete computer model of an organism, which can use computer-aided design for better diagnosis and treatment of diseases.


http://cdn.physorg.com/newman/gfx/news/hires/2012/3-stanfordrese.jpg

                      The covert lab incorporated more than 1,900 experimentally
                                   observed parameter into their model of the tiny
                                     parasite Mycoplasma  genitalium illustration
                                                :- Erik Jac obsen / Covert Lab

 It may not be too long before computers can accurately simulate complex life forms such as houseflies, and one day, even humans. In the first step towards computer simulation of life, scientists from Stanford University have developed the world's first computational model of a living organism, the bacteria, Mycoplasma genitalium.

(Phys.org) -- In a breakthrough effort for computational biology, the world's first complete computer model of an organism has been completed, Stanford researchers reported in the journal Cell.

Read more at: http://phys.org/news/2012-07-researchers-produce-first-complete-computer.html#jCp
The Covert Lab incorporated more than 1,900 experimentally observed parameters into their model of the tiny parasite Mycoplasma genitalium. Illustration: Erik Jacobsen / Covert Lab

Read more at: http://phys.org/news/2012-07-researchers-produce-first-complete-computer.html#jCp
The Covert Lab incorporated more than 1,900 experimentally observed parameters into their model of the tiny parasite Mycoplasma genitalium. Illustration: Erik Jacobsen / Covert Lab

Read more at: http://phys.org/news/2012-07-researchers-produce-first-complete-computer.html#jCp
A team of Stanford researchers , including an Indian, used data from more than 900 scientific papers to account for every molecular interaction that takes place in the life cycle of Mycoplasma genitalium, the world's smallest free-living bacterium.Scientists have recreated life with the world’s first computer model of a complete living organism.
Mycoplasma genitalium might be the world's smallest free-living bacterium, but modelling every single molecular interaction has been a massive task.
Researchers playing God at Stanford University used data from over 900 scientific papers to create the computer model of the parasitic bacterium, opening the door for computer aided design in bioengineering and medicine.
The final virtual cell model made use of more than 1,900 experimentally determined parameters, with computational models making sense of “enormous” amounts of data, according to the scientists.
This can kick start computer aided design using the model developed can now begin, and could even mean the “wholesale creation of new microorganisms”.
Bacteria or yeast could be used to mass produce pharmaceuticals, for example, or personalised medicine.  
The created bacterium is only 525 genes large, compared to E.Coli which is a tad more complicated at 4,288, but it seems the researchers will begin looking to model larger organisms too in the future.
That is not to say that we are in the realms of 80s sci-fi flick Weird Science just yet. The scientists say that even medicinal applications are a long way off, and it is going to take an effort on the level of the Human Genome Project to get close to a human mode.

 Creation being a tough act to follow when it comes to The Living-but-Dead [but not for The Living, of course], perhaps creativity is easier on the conscience of those who are unconscionable. As such, would the addition of some app to do this or that to a PhonyPoddyPaddy be classifiable as creating a new PhonyPoddyPaddy? Make you 'fink, ain't eet.

For those whose ambition in life is to count beyond their toes, life is not only a miracle, it is actually sacred and is therefore not at all creatable by any ole energy transformer, absolute transformation being the realisation of a human from a single cellular entity. Some "Protein XYZ" might be able to alter the principle of, say, a liver cell to some concept of a cancer by "democratising" that cell with new and wonderful concepts about "individuality", "entertainment", and "concerting" [where chemistry, biology and perhaps physics, is free flowing], but that is not about creation, it is all about creativity. A Simplicity which Eludes, especially those whose qik-fix in life in to add zeroes to anything and calling that creativity, creation, the addition of enough zeroes, meaning nothing, being the path to Infinity for the vacuous Infintisers. Yet Another Simplicity which Eludes. Perhaps this is why nothing is also everything, the power of the atom being the proof. ASWE.

At this rate of elusivity, humans will be reduced to something beyond our stupdity-dumbness, humans being the result of [Cosmic] Dust. If true, where did Conscience came from? Permutations and Combinations perhaps, the fav of Statisticians, oka Gamblers Galore. You cannot "re-create" something which is living although you could modify it, such is rationality, the grasping at reality by the vacuous, much like those born blind trying to hold onto their concept of colours just in case their lack of conscience is uncovered, Conscience being the consciousness and then awareness that one is human - a case of introspection/self/creation and not its superficial substitute, inspection/another/re-creation/creativity.

As such, those who have conscience will never, ever, imagine for a moment, that creativity is creation. ASWE, especially for "Creationists", those who have yet to realised Divinity other than re-presenting their concept of Divinity in the hopes of obtaining a seat at The Final Photoshoot. And why are "pro-God-dists" bad for The Divine? Because they promote imagination and belief systems, oka Religion & Religiosity, which any ole human will be able to discern is untrue thereby casting Divinity into mythology if not one belonging to The Asylum too. Above all else, the hardening of concepts will thwart attempts by Principles [of Divinity] to maintaining their course. The Bookie not only profits through/from Disagreement, He is a very, very, sly Devil too. So cunning that any attempt at realising Reality through thoughts meant that He's got you before you had even begun. One reason why Divinity is for, and realisable by, all like the deprived, the infirmed, the blind-blinded, the "uneducated", and the young and not only by scholarship.

In fact and in reality, it is easier for a camel to pass through the eye of needle than for a scholar/preacher to realise The Divine, something zombies who religiously attend religious gatherings never, ever, hear about. Why is this so? Because The Devil is not only in The Details, The Devil is The Details, oka one's thoughts [of The Past and The Future], symbolised as The 2 Horns of The Devil and His hold on The Trident, The 3 Dimensionalities [out of 5] that are within reach of any ole human, namely one's Subjectivity/The Past/"The Left"/Femininity, and Objectivity-Projectivity/The Future/"The Right"/Masculinity.
A team led by Stanford bioengineering Professor Markus Covert used data from more than 900 scientific papers to account for every molecular interaction that takes place in the life cycle of Mycoplasma genitalium – the world's smallest free-living bacterium. By encompassing the entirety of an organism in silicon, the paper fulfills a longstanding goal for the field. Not only does the model allow researchers to address questions that aren't practical to examine otherwise, it represents a stepping-stone toward the use of computer-aided design in bioengineering and medicine. "This achievement demonstrates a transforming approach to answering questions about fundamental biological processes," said James M. Anderson, director of the National Institutes of Health Division of Program Coordination, Planning and Strategic Initiatives. "Comprehensive computer models of entire cells have the potential to advance our understanding of cellular function and, ultimately, to inform new approaches for the diagnosis and treatment of disease."

Read more at: http://phys.org/news/2012-07-researchers-produce-first-complete-computer.html#jCp
A team led by Stanford bioengineering Professor Markus Covert used data from more than 900 scientific papers to account for every molecular interaction that takes place in the life cycle of Mycoplasma genitalium – the world's smallest free-living bacterium. By encompassing the entirety of an organism in silicon, the paper fulfills a longstanding goal for the field. Not only does the model allow researchers to address questions that aren't practical to examine otherwise, it represents a stepping-stone toward the use of computer-aided design in bioengineering and medicine.

Read more at: http://phys.org/news/2012-07-researchers-produce-first-complete-computer.html#jCp
The Covert Lab incorporated more than 1,900 experimentally observed parameters into their model of the tiny parasite Mycoplasma genitalium. Illustration: Erik Jacobsen / Covert Lab

Read more at: http://phys.org/news/2012-07-researchers-produce-first-complete-computer.html#jCp
(Phys.org) -- In a breakthrough effort for computational biology, the world's first complete computer model of an organism has been completed, Stanford researchers reported in the journal Cell.

Read more at: http://phys.org/news/2012-07-researchers-produce-first-complete-computer.html#jCp
The Covert Lab incorporated more than 1,900 experimentally observed parameters into their model of the tiny parasite Mycoplasma genitalium. Illustration: Erik Jacobsen / Covert Lab

Read more at: http://phys.org/news/2012-07-researchers-produce-first-complete-computer.html#jCp
The Covert Lab incorporated more than 1,900 experimentally observed parameters into their model of the tiny parasite Mycoplasma genitalium. Illustration: Erik Jacobsen / Covert Lab

Read more at: http://phys.org/news/2012-07-researchers-produce-first-complete-computer.html#jC
(Phys.org) -- In a breakthrough effort for computational biology, the world's first complete computer model of an organism has been completed, Stanford researchers reported in the journal Cell.

Read more at: http://phys.org/news/2012-07-researchers-produce-first-complete-computer.html#jCp
the world's first complete computer model of an organism has been completed, Stanford researchers reported in the journal Cell.

Read more at: http://phys.org/news/2012-07-researchers-produce-first-complete-computer.html#jCp






source : TOI,and Stanford researchers

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

(Phys.org) -- In a breakthrough effort for computational biology, the world's first complete computer model of an organism has been completed, Stanford researchers reported in the journal Cell.

Read more at: http://phys.org/news/2012-07-researchers-produce-first-complete-computer.html#jCp
In a breakthrough effort for computational biology, the world's first complete computer model of an organism has been completed, Stanford researchers reported in the journal Cell.

Read more at: http://phys.org/news/2012-07-researchers-produce-first-complete-computer.html#jCp
In a breakthrough effort for computational biology, the world's first complete computer model of an organism has been completed, Stanford researchers reported in the journal Cell.

Read more at: http://phys.org/news/2012-07-researchers-produce-first-complete-computer.html#jCp

No comments:

Post a Comment

Related Posts Plugin for WordPress, Blogger...

Love 4 Bihar on Facebook